Review



curve fitting tool (cftool)  (MathWorks Inc)


Bioz Verified Symbol MathWorks Inc is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    MathWorks Inc curve fitting tool (cftool)
    Curve Fitting Tool (Cftool), supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/curve fitting tool (cftool)/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    curve fitting tool (cftool) - by Bioz Stars, 2026-03
    90/100 stars

    Images



    Similar Products

    displacement curve fitting  (Malvern Panalytical)
    99
    Malvern Panalytical displacement curve fitting
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Displacement Curve Fitting, supplied by Malvern Panalytical, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/displacement curve fitting/product/Malvern Panalytical
    Average 99 stars, based on 1 article reviews
    displacement curve fitting - by Bioz Stars, 2026-03
    99/100 stars
    		  Buy from Supplier
    curve fitting tool (cftool)  (MathWorks Inc)
    90
    MathWorks Inc curve fitting tool (cftool)
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Curve Fitting Tool (Cftool), supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/curve fitting tool (cftool)/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    curve fitting tool (cftool) - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    belysa immunoassay curve fitting software  (Millipore)
    90
    Millipore belysa immunoassay curve fitting software
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Belysa Immunoassay Curve Fitting Software, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/belysa immunoassay curve fitting software/product/Millipore
    Average 90 stars, based on 1 article reviews
    belysa immunoassay curve fitting software - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    curve fitting tool  (MathWorks Inc)
    90
    MathWorks Inc curve fitting tool
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Curve Fitting Tool, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/curve fitting tool/product/MathWorks Inc
    Average 90 stars, based on 1 article reviews
    curve fitting tool - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    non-linear regression curve fit analysis using graphpad prism software version 5.01  (GraphPad Software Inc)
    90
    GraphPad Software Inc non-linear regression curve fit analysis using graphpad prism software version 5.01
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Non Linear Regression Curve Fit Analysis Using Graphpad Prism Software Version 5.01, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/non-linear regression curve fit analysis using graphpad prism software version 5.01/product/GraphPad Software Inc
    Average 90 stars, based on 1 article reviews
    non-linear regression curve fit analysis using graphpad prism software version 5.01 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    non-linear curve fitting in graphpad prism  (GraphPad Software Inc)
    90
    GraphPad Software Inc non-linear curve fitting in graphpad prism
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Non Linear Curve Fitting In Graphpad Prism, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/non-linear curve fitting in graphpad prism/product/GraphPad Software Inc
    Average 90 stars, based on 1 article reviews
    non-linear curve fitting in graphpad prism - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    non-linear curve fitting  (GraphPad Software Inc)
    90
    GraphPad Software Inc non-linear curve fitting
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Non Linear Curve Fitting, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/non-linear curve fitting/product/GraphPad Software Inc
    Average 90 stars, based on 1 article reviews
    non-linear curve fitting - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    nonlinear regression curve fitting  (GraphPad Software Inc)
    90
    GraphPad Software Inc nonlinear regression curve fitting
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Nonlinear Regression Curve Fitting, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nonlinear regression curve fitting/product/GraphPad Software Inc
    Average 90 stars, based on 1 article reviews
    nonlinear regression curve fitting - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier
    curve-fitting software graphpad prism 10.3.1  (GraphPad Software Inc)
    90
    GraphPad Software Inc curve-fitting software graphpad prism 10.3.1
    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC <t>displacement</t> experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .
    Curve Fitting Software Graphpad Prism 10.3.1, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/curve-fitting software graphpad prism 10.3.1/product/GraphPad Software Inc
    Average 90 stars, based on 1 article reviews
    curve-fitting software graphpad prism 10.3.1 - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC displacement experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .

    Journal: iScience

    Article Title: DNA-encoded library screening uncovers potent DNMT2 inhibitors targeting a cryptic allosteric binding site

    doi: 10.1016/j.isci.2025.113300

    Figure Lengend Snippet: Investigating the ligand binding mode and selectivity with biophysical methods (A) Chemical structures of probe 8 : TAMRA-labeled β-homo-tripeptide. (B) MST dose-response curves for probe 8 binding to DNMT2. (C) Fluorescence polarization assay for probe 6 binding to native DNMT2 (2 μM), DNMT2 (2 μM) preincubated with SAH (100 μM), DNMT2 (2 μM) with tRNA Asp (10 μM), and various related MTase off-targets (all 2 μM). (D) DNMT2-SAH ITC displacement experiment for compound 3 . SAH was titrated to DNMT2 in the absence resp. presence of compound 3 (100 μM), yielding a significant enthalpy reduction. (E) EMSA assay investigates the competition of hit compounds 1 – 5 with the tRNA substrate. Positive control: tRNA+DNMT2 (band at high molecular weights); negative control: only tRNA (band at low molecular weights). Hit compounds 1 – 5 (100 μM) were added to the DNMT2-tRNA complex (10 + 5 μM) and analyzed by native PAGE. No compound was able to dissociate the DNMT2-tRNA complex. Data are represented as mean ± SEM. Uncropped PAGE images can be found in .

    Article Snippet: Data analysis and displacement curve fitting were accomplished via the MicroCal PEAQ-ITC Analysis Software.

    Techniques: Ligand Binding Assay, Labeling, Binding Assay, Fluorescence, Positive Control, Negative Control, Clear Native PAGE